SCHEMBL1366727

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4636340	0.87	GABRA5 (0.55)	CARM1PRMT6HPGDSPRKAB2PRKAG1
	SCHEMBL1366200	0.85	HPGDS (0.54)	CARM1PRMT6HPGDSPRKAB2PRKAG1
	SCHEMBL1366534	0.85	PRKAA2 (0.75)	PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3
	SCHEMBL1367082	0.83	HPGDS (0.78)	CARM1PRMT6HPGDSPRKAB2PRKAG1
	SCHEMBL14094612	0.83	CKS1B (0.54)	CARM1PRMT6HPGDSPRKAB2PRKAG1
	SCHEMBL1366027	0.81	HPGDS (0.58)	HPGDSADRA1DADRA1AADRA1BSSTR5
	SCHEMBL1366327	0.81	GABRA5 (0.57)	HPGDSPRKAB2PRKAG1PRKAA2PRKAA1
	SCHEMBL1367196	0.81	DRD4 (0.67)	HPGDSPRKAB2PRKAG1PRKAA2PRKAA1
	SCHEMBL1366963	0.80	SLC6A12 (0.57)	HPGDSPRKAB2PRKAG1PRKAA2PRKAA1
	SCHEMBL10251883	0.79	CXCR4 (0.74)	PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.