Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13669850 | 0.83 | MAPT (0.51) | KMT2AMAPTMEN1GABRA1GABRB2 | |
| SCHEMBL5593166 | 0.81 | CTSD (0.50) | KMT2AMAPTMEN1GABRA1GABRB2 | |
| SCHEMBL28577924 | 0.81 | LMNA (0.56) | KMT2AMAPTMEN1SMN1; SMN2MAOA | |
| SCHEMBL30561252 | 0.81 | MAPT (0.45) | KMT2AMAPTMEN1SMN1; SMN2PSEN1 | |
| SCHEMBL26200366 | 0.80 | MAPT (0.49) | KMT2AMAPTMEN1SMN1; SMN2MAOA | |
| SCHEMBL3065368 | 0.80 | KMT2A (0.49) | KMT2AMAPTMEN1SMN1; SMN2MAOA | |
| SCHEMBL6748722 | 0.78 | MAPT (0.61) | KMT2AMAPTMEN1SMN1; SMN2MAOA | |
| SCHEMBL11545937 | 0.77 | CAPN1 (0.52) | KMT2AMAPTMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2257068 | 0.77 | GABRA1 (0.52) | KMT2AMAPTMEN1GABRA1GABRB2 | |
| SCHEMBL6628172 | 0.77 | CSNK1E (0.42) | KMT2AMAPTMEN1PSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090263405-A1 | CpG OLIGONUCLEOTIDE PRODRUGS, COMPOSITIONS THEREOF AND ASSOCIATED THERAPEUTIC METHODS | GOVERNMENT OF THE UNITED STATES OF AMERICA REPRESENTED BY THE SECRETARY (US) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090263405-A1 | CpG OLIGONUCLEOTIDE PRODRUGS, COMPOSITIONS THEREOF AND ASSOCIATED THERAPEUTIC METHODS | TYMP, DCTD, TET1 | KMT2A 2152/4885MAPT 2930/4885MEN1 4189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.