Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13669850 | 0.86 | MAPT (0.51) | MAPTKMT2AMEN1SMN1; SMN2MAOA | |
| SCHEMBL28577924 | 0.84 | LMNA (0.56) | MAPTKMT2AMEN1SMN1; SMN2MAOA | |
| SCHEMBL3065368 | 0.83 | KMT2A (0.49) | MAPTKMT2AMEN1SMN1; SMN2MAOA | |
| SCHEMBL6748722 | 0.81 | MAPT (0.61) | MAPTKMT2AMEN1SMN1; SMN2MAOA | |
| SCHEMBL13670100 | 0.80 | KMT2A (0.50) | MAPTKMT2AMEN1SMN1; SMN2MAOA | |
| SCHEMBL11545937 | 0.80 | CAPN1 (0.52) | MAPTKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11544239 | 0.79 | HPGD (0.50) | MAPTKMT2AMEN1SMN1; SMN2MAOA | |
| SCHEMBL5048768 | 0.78 | FOLH1 (0.53) | MAPTSMN1; SMN2ALDH1A1KDM4EHTT | |
| SCHEMBL19407976 | 0.77 | ALDH1A1 (0.58) | MAPTKMT2AALDH1A1POLBKDM4E | |
| SCHEMBL25056676 | 0.77 | RIPK1 (0.41) | ALDH1A1HTTTSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230271998-A1 | SOLID SUPPORT FOR SYNTHESIZING NUCLEIC ACID SEQUENCES AND METHODS FOR MAKING AND USING | UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2023-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230271998-A1 | SOLID SUPPORT FOR SYNTHESIZING NUCLEIC ACID SEQUENCES AND METHODS FOR MAKING AND USING | RNGTT, NSUN2, POLN | MAPT 4759/4885KMT2A 971/4885MEN1 625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.