Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 15/20 | 0.67 |
| ▸ | DRD1 | P21728 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | LOX | P28300 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5723494 | 0.87 | PTGS2 (0.65) | PTGS2DRD1PTGS1 | |
| SCHEMBL8604437 | 0.84 | PTGS2 (0.61) | PTGS2DRD1PTGS1 | |
| SCHEMBL29155280 | 0.84 | ALDH1A1 (0.47) | PTGS2DRD1PTGS1LOX | |
| SCHEMBL27573095 | 0.84 | CA2 (0.64) | PTGS2DRD1PTGS1 | |
| SCHEMBL8604252 | 0.83 | PTGS2 (0.59) | PTGS2DRD1PTGS1 | |
| SCHEMBL6048541 | 0.83 | PTGS2 (0.59) | PTGS2DRD1PTGS1 | |
| Hydrochloric Acid SCHEMBL6048552 | 0.82 | PTGS2 (0.57) | PTGS2DRD1PTGS1 | |
| SCHEMBL9890741 | 0.80 | PTGS2 (0.56) | PTGS2DRD1PTGS1 | |
| SCHEMBL5502727 | 0.80 | PTGS2 (1.00) | PTGS2PTGS1 | |
| Hydrogen Sulfide SCHEMBL27744400 | 0.79 | PTGS2 (0.96) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270381-A1 | Non-steroidal progesterone receptor modulators | BAYER SCHERING PHARMA AG (DE) | 2009-10-29 | — | — | US | disclosed |
| US-20090075989-A1 | NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS | BAYER SCHERING PHARMA AG (DE) | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270381-A1 | Non-steroidal progesterone receptor modulators | PGR, PGRMC1, PGRMC2 | PTGS2 48/4885DRD1 3528/4885PTGS1 21/4885 |
| US-20090075989-A1 | NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS | NR5A1, CYP19A1, GPER1 | PTGS2 72/4885DRD1 2883/4885PTGS1 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.