Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3844145 | 0.77 | PTGDR2 (0.52) | PTGDR2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL13675569 | 0.76 | ALOX5 (0.52) | PTGDR2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL3823856 | 0.76 | TRPM8 (0.56) | PTGDR2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL13675833 | 0.71 | MAPT (0.42) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL13675568 | 0.70 | L3MBTL1 (0.45) | PTGDR2ALDH1A1KDM4EHPGD | |
| SCHEMBL13675694 | 0.68 | CLK4 (0.52) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL6436649 | 0.67 | MAPT (0.53) | PTGDR2KDRMAPTMEN1KMT2A | |
| SCHEMBL2756231 | 0.66 | ALDH1A1 (0.59) | PTGDR2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL10160621 | 0.66 | MAPT (0.71) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL4559287 | 0.66 | MAPT (0.52) | KDRMAPTALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270456-A1 | Novel chemical compounds | HASEGAWA MASAICHI | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270456-A1 | Novel chemical compounds | HIPK3, HIPK2, HIPK1 | PTGDR2 3859/4885KDR 3951/4885MAPT 1801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.