Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SULT1A1 | P50225 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13675685 | 0.84 | MAPT (0.50) | PTGDR2KDM4ERAB9ASMN1; SMN2MAPT | |
| SCHEMBL13675585 | 0.76 | PTGDR2 (0.47) | ALOX5PTGDR2KDM4ERAB9ANPC1 | |
| SCHEMBL2756231 | 0.72 | ALDH1A1 (0.59) | PTGDR2KDM4EPRMT1POLBMAPT | |
| SCHEMBL1567358 | 0.72 | PTPN11 (0.51) | ALOX5PTGDR2KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL13675487 | 0.71 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL13801084 | 0.70 | KDM4E (0.61) | ALOX5PTGDR2KDM4ERAB9ANPC1 | |
| SCHEMBL8005690 | 0.70 | PTGDR2 (0.68) | ALOX5PTGDR2KDM4ERAB9ANPC1 | |
| SCHEMBL3830437 | 0.70 | TRPM8 (0.54) | ALOX5PTGDR2KDM4ERAB9ANPC1 | |
| SCHEMBL2756230 | 0.69 | PTGDR2 (0.44) | PTGDR2KDM4EPRMT1MAPTALDH1A1 | |
| SCHEMBL28295525 | 0.69 | ALOX5 (0.60) | ALOX5PTGDR2PRMT1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270456-A1 | Novel chemical compounds | HASEGAWA MASAICHI | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270456-A1 | Novel chemical compounds | HIPK3, HIPK2, HIPK1 | ALOX5 4697/4885PTGDR2 3859/4885KDM4E 3251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.