SCHEMBL1367594

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1365716	0.89	JAK2 (0.52)	JAK2JAK3JAK1TYK2SYK
	SCHEMBL1365720	0.89	JAK2 (0.52)	JAK2JAK3JAK1TYK2SYK
	SCHEMBL1368609	0.88	JAK2 (0.51)	JAK2JAK3JAK1TYK2KDM4E
	SCHEMBL1368605	0.88	JAK2 (0.51)	JAK2JAK3JAK1TYK2KDM4E
	Hydrochloric Acid SCHEMBL1368931	0.88	JAK2 (0.51)	JAK2JAK3JAK1TYK2KDM4E
	Hydrochloric Acid SCHEMBL1368927	0.88	JAK2 (0.51)	JAK2JAK3JAK1TYK2KDM4E
	SCHEMBL15436282	0.86	JAK2 (0.51)	JAK2JAK3JAK1TYK2KDM4E
	SCHEMBL1368007	0.85	JAK2 (0.55)	JAK2JAK3JAK1TYK2KCNH2
	SCHEMBL1368012	0.85	JAK2 (0.55)	JAK2JAK3JAK1TYK2KCNH2
	SCHEMBL30007484	0.85	JAK2 (0.53)	JAK2JAK3JAK1TYK2KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.