Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 3/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 3/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12670047 | 1.00 | MMP3 (0.42) | MMP3ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL14374830 | 0.82 | MMP3 (0.32) | MMP3MMP9 | |
| SCHEMBL13127084 | 0.81 | CTSS (0.31) | CTSSCTSK | |
| SCHEMBL22872358 | 0.81 | CTSS (0.31) | CTSSCTSK | |
| SCHEMBL14374847 | 0.81 | — | — | |
| SCHEMBL14306752 | 0.79 | MMP3 (0.31) | MMP3 | |
| SCHEMBL13676317 | 0.79 | MMP3 (0.31) | MMP3 | |
| SCHEMBL12191402 | 0.79 | ALDH1A1 (0.41) | MMP3ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL22059701 | 0.78 | CTSL (0.36) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL12250761 | 0.78 | ALDH1A1 (0.39) | ALDH1A1MEN1LMNAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312211-B2 | Pryanone compounds useful as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2007-12-25 | — | — | US | disclosed |