SCHEMBL13679127

SCHEMBL13679127

O=C(OCCCCCCOC(=O)C1=C(c2ccccc2)C(=O)c2ccccc2C1=O)C1=C(c2ccccc2)C(=O)c2ccccc2C1=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 5/20 0.56
MEN1 O00255 4/20 0.56
LMNA P02545 4/20 0.56
KMT2A Q03164 4/20 0.56
SMN1; SMN2 Q16637 4/20 0.56
ALDH1A1 P00352 4/20 0.56
TDP1 Q9NUW8 4/20 0.56
MAPT P10636 4/20 0.56
HTT P42858 4/20 0.56
HSP90AA1 P07900 3/20 0.56
HKDC1 Q2TB90 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
KDM4E B2RXH2 2/20 0.56
NPC1 O15118 2/20 0.56
MAPK1 P28482 2/20 0.56
MPI P34949 2/20 0.56
RAB9A P51151 2/20 0.56
TP53 P04637 1/20 0.56
HSP90AB1 P08238 1/20 0.56
FGFR1 P11362 6/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15827661 1.00 NPSR1 (0.56) NPSR1MEN1LMNAKMT2ASMN1; SMN2
SCHEMBL17969781 0.84 ALDH1A1 (0.78) NPSR1MEN1LMNAKMT2ASMN1; SMN2
SCHEMBL8340214 0.82 MAPT (0.56) NPSR1MEN1LMNAKMT2ASMN1; SMN2
SCHEMBL445362 0.82 ALDH1A1 (0.56) NPSR1MEN1LMNAKMT2ASMN1; SMN2
SCHEMBL17969780 0.78 FGFR1 (0.88) NPSR1MEN1LMNAKMT2ASMN1; SMN2
SCHEMBL7538581 0.78 PPARG (0.72) NPSR1MEN1LMNAKMT2ASMN1; SMN2
SCHEMBL19446018 0.77 HSP90AA1 (0.61) NPSR1MEN1LMNAKMT2ASMN1; SMN2
SCHEMBL12382276 0.77 HSP90AA1 (0.61) NPSR1MEN1LMNAKMT2ASMN1; SMN2
SCHEMBL21470361 0.77 ALDH1A1 (0.54) NPSR1MEN1LMNAKMT2ASMN1; SMN2
SCHEMBL21470357 0.77 MAPT (0.57) NPSR1MEN1LMNAKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1621934-B1 Electrophotographic photoconductor for wet developing and image-forming apparatus for wet-developing KYOCERA MITA CORP (JP) 2009-09-09 EP disclosed