Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.36 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.33 |
| ▸ | RRM1 | P23921 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.32 |
| ▸ | GABRD | O14764 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13958540 | 0.80 | HDAC7 (0.40) | DPP7HDAC7HDAC8HDAC6HDAC9 | |
| SCHEMBL6848366 | 0.80 | HDAC7 (0.40) | DPP7HDAC7HDAC8HDAC6HDAC9 | |
| SCHEMBL13227770 | 0.76 | HDAC7 (0.43) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL25719293 | 0.76 | HDAC7 (0.43) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL12766447 | 0.76 | HDAC7 (0.36) | DPP7HDAC7HDAC8HDAC6HDAC9 | |
| SCHEMBL22175192 | 0.76 | TDP1 (0.47) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL22622376 | 0.74 | HDAC7 (0.35) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL18964732 | 0.74 | SIRT6 (0.38) | DPP7HDAC7HDAC8HDAC6HDAC9 | |
| SCHEMBL11652880 | 0.73 | ANPEP (0.37) | DPP7SLC15A1ANPEPDNPEPDPP4 | |
| SCHEMBL3867719 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2103619-A1 | IMIDAZOTHIAZOLE DERIVATIVES | Daiichi Sankyo Company, Limited (JP) | 2009-09-23 | — | — | EP | disclosed |