Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.38 |
| ▸ | PPARA | Q07869 | 5/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6473031 | 0.84 | AKR1B1 (0.42) | CTBP2AKR1B1 | |
| Hydrogen Peroxide SCHEMBL29092952 | 0.84 | LIPG (0.45) | PPARGPPARALIPGHTR1AADRA2A | |
| SCHEMBL6547299 | 0.82 | MAOA (0.40) | PPARGPPARA | |
| SCHEMBL14700051 | 0.82 | DAO (0.37) | PPARGPPARACTBP2 | |
| Benzene SCHEMBL11786397 | 0.82 | KDM4E (0.44) | PPARGPPARALIPGHTR1AADRA2A | |
| SCHEMBL5863279 | 0.81 | PPARA (0.40) | PPARGPPARACTBP2AKR1B1 | |
| SCHEMBL4032382 | 0.79 | AKR1B1 (0.57) | PPARGPPARAKDM4EALDH1A1HPGD | |
| SCHEMBL142479 | 0.79 | ADRA2B (0.44) | PPARGPPARALIPGHTR1AADRA2A | |
| SCHEMBL29488434 | 0.79 | ADRA2B (0.44) | PPARGPPARALIPGHTR1AADRA2A | |
| SCHEMBL12802271 | 0.79 | THRB (0.38) | PPARGPPARALIPGHTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1411046-B1 | QUINOLINE DERIVATIVE AND QUINAZOLINE DERIVATIVE INHIBITING SELF-PHOSPHORYLATION OF HEPATOCYTUS PROLIFERATOR RECEPTOR, AND MEDICINAL COMPOSITION CONTAINING THE SAME | KIRIN PHARMA KK (JP) | 2009-09-16 | — | — | EP | disclosed |