Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.39 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | JUN | P05412 | 1/20 | 0.38 |
| ▸ | IAPP | P10997 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661727 | 0.89 | MAPT (0.47) | LMNATDP1MEN1KMT2AMAPT | |
| SCHEMBL14279465 | 0.82 | LMNA (0.66) | LMNATDP1MEN1THRBBLM | |
| SCHEMBL1499959 | 0.78 | RAB9A (0.59) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL2961735 | 0.78 | TSHR (0.45) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL10962113 | 0.78 | MAPT (0.66) | LMNATDP1MAPTTRIM24TRIM33 | |
| SCHEMBL8349013 | 0.78 | TSHR (0.45) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8295301 | 0.76 | MAPT (0.40) | LMNATDP1MEN1KMT2AMAPT | |
| SCHEMBL7198619 | 0.76 | PTPN1 (0.46) | LMNATDP1BLMMAPTALDH1A1 | |
| SCHEMBL2313840 | 0.75 | NFKB1 (0.64) | LMNATDP1MEN1THRBBLM | |
| SCHEMBL30451096 | 0.75 | NFKB1 (0.64) | LMNATDP1MEN1THRBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582123-B2 | Coloring composition comprising at least one azomethine compound with a pyrazolinone unit | L'OREAL S.A. (FR) | 2009-09-01 | — | — | US | disclosed |