SCHEMBL2961735

SCHEMBL2961735

C=C(C)C=Cc1ccccc1C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 3/20 0.45
▸ ALDH1A1 P00352 2/20 0.45
▸ RAB9A P51151 4/20 0.42
▸ KDM4E B2RXH2 3/20 0.42
▸ APOBEC3A P31941 1/20 0.42
▸ APOBEC3G Q9HC16 1/20 0.42
▸ LMNA P02545 2/20 0.41
▸ MAPT P10636 1/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ PABPC1 P11940 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ TP53 P04637 1/20 0.39
▸ CYP1A2 P05177 1/20 0.39
▸ CYP2D6 P10635 1/20 0.39
▸ THPO P40225 1/20 0.39
▸ HIF1A Q16665 1/20 0.39
▸ NR1H2 P55055 1/20 0.39
▸ NR1H3 Q13133 1/20 0.39
▸ GMNN O75496 1/20 0.37
▸ PMP22 Q01453 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8349013 1.00 TSHR (0.45) TSHRALDH1A1RAB9AKDM4EAPOBEC3A
SCHEMBL8661727 0.87 MAPT (0.47) ALDH1A1RAB9AKDM4ELMNAMAPT
SCHEMBL8859640 0.83 ALDH1A1 (0.45) TSHRALDH1A1RAB9AKDM4EAPOBEC3A
SCHEMBL13816225 0.82 TSHR (0.43) TSHRALDH1A1RAB9AKDM4EAPOBEC3A
SCHEMBL17682919 0.82 TSHR (0.43) TSHRALDH1A1RAB9AKDM4EAPOBEC3A
SCHEMBL16507826 0.81 CD44 (0.41) TSHRALDH1A1KDM4ELMNAMAPT
SCHEMBL12809932 0.81 LMNA (0.44) TSHRALDH1A1RAB9AKDM4EAPOBEC3A
SCHEMBL20373431 0.80 TSHR (0.42) TSHRALDH1A1RAB9AKDM4EAPOBEC3A
SCHEMBL3437259 0.80 TSHR (0.42) TSHRALDH1A1RAB9AKDM4EAPOBEC3A
SCHEMBL7899013 0.79 MAPT (0.66) TSHRALDH1A1RAB9AKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7776975-B2 Aqueous polymerization process for preparing an aqueous polymer dispersion ROHM AND HAAS COMPANY (US) 2010-08-17 — — US claimed
US-7776975-B2 Aqueous polymerization process for preparing an aqueous polymer dispersion ROHM AND HAAS COMPANY (US) 2010-08-17 — — US disclosed
US-7772318-B2 very low low molecular weight polymer particles and high molecular weight polymer particles; addition polymer; latex paint ROHM AND HAAS COMPANY (US) 2010-08-10 — — US disclosed
EP-1710284-B1 Aqueous polymer dispersions ROHM & HAAS (US) 2008-02-27 — — EP disclosed
EP-1498430-B1 Aqueous polymerization process for preparing an aqueous polymer dispersion ROHM & HAAS (US) 2007-09-12 — — EP disclosed
EP-1710284-A1 Aqueous polymer dispersions ROHM AND HAAS COMPANY (US) 2006-10-11 — — EP disclosed
US-20060223935-A1 Aqueous polymer dispersions ROHM AND HAAS COMPANY 2006-10-05 — — US disclosed
US-20050014883-A1 Aqueous polymerization process for preparing an aqueous polymer dispersion Patent Department 2005-01-20 — — US disclosed
EP-1498430-A1 Aqueous polymerization process for preparing an aqueous polymer dispersion ROHM AND HAAS COMPANY (US) 2005-01-19 — — EP disclosed
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