Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14502540 | 0.88 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1GAAKMT2AL3MBTL1 | |
| SCHEMBL11489686 | 0.79 | SIRT1 (0.54) | ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL2295833 | 0.78 | ALDH1A1 (0.74) | SMN1; SMN2ALDH1A1GAAATMKMT2A | |
| Hydrochloric Acid SCHEMBL7110024 | 0.76 | ALDH1A1 (0.77) | SMN1; SMN2ALDH1A1GAAATMKMT2A | |
| SCHEMBL1092652 | 0.75 | TRPM8 (0.42) | SMN1; SMN2ALDH1A1L3MBTL1PKMKDM4E | |
| SCHEMBL307472 | 0.75 | P2RX7 (0.50) | SMN1; SMN2ALDH1A1L3MBTL1KDM4ELMNA | |
| SCHEMBL5087696 | 0.75 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1GAAATMKMT2A | |
| SCHEMBL7110016 | 0.75 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1GAAATMKMT2A | |
| SCHEMBL781008 | 0.75 | NAPRT (0.56) | SMN1; SMN2ALDH1A1KMT2AL3MBTL1KDM4E | |
| SCHEMBL257468 | 0.74 | LMNA (0.54) | SMN1; SMN2KMT2AL3MBTL1PKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582664-B2 | Acylaminothiazole derivatives, preparation method thereof and use of same in therapeutics | SANOFI-AVENTIS (FR) | 2009-09-01 | — | — | US | disclosed |
| US-7582664-B2 | Acylaminothiazole derivatives, preparation method thereof and use of same in therapeutics | SANOFI-AVENTIS (FR) | 2009-09-01 | — | — | US | disclosed |