Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 2/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680487 | 0.85 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2APPARANPC1 | |
| SCHEMBL13680478 | 0.85 | KDM4E (0.62) | ALDH1A1MEN1KMT2APPARANPC1 | |
| SCHEMBL13680733 | 0.83 | CYP2E1 (0.45) | TGFBR1ALDH1A1PPARANPC1RAB9A | |
| SCHEMBL13681289 | 0.83 | PPARA (0.46) | ALDH1A1MEN1KMT2APPARANPC1 | |
| SCHEMBL8198560 | 0.82 | CYP3A4 (0.60) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL31341074 | 0.81 | MKNK1 (0.50) | PIM1PIM3ALDH1A1MEN1KMT2A | |
| SCHEMBL13680524 | 0.81 | MAPT (0.58) | ALDH1A1MEN1KMT2APPARANPC1 | |
| SCHEMBL13680527 | 0.81 | RAB9A (0.66) | ALDH1A1MEN1KMT2APPARANPC1 | |
| SCHEMBL13680528 | 0.81 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2APPARANPC1 | |
| SCHEMBL7905176 | 0.80 | CYP3A4 (0.58) | ALDH1A1MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |