Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 8/20 | 0.59 |
| ▸ | CACNG8 | Q8WXS5 | 8/20 | 0.59 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.50 |
| ▸ | CCR1 | P32246 | 1/20 | 0.47 |
| ▸ | CCR8 | P51685 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | CDC25A | P30304 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.45 |
| ▸ | CDC25C | P30307 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.45 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.45 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15638158 | 0.81 | TGFBR1 (0.50) | GRIA1CACNG8PDE3BPDE3ATGFBR1 | |
| SCHEMBL13680450 | 0.80 | CA12 (0.53) | GRIA1CACNG8PDE3BPDE3ACCR1 | |
| SCHEMBL13680565 | 0.78 | PDE3B (0.54) | PDE3BPDE3ACCR1CCR8CYP2A6 | |
| SCHEMBL13680559 | 0.76 | RAB9A (0.56) | CCR1CCR8CYP2A6TGFBR1 | |
| SCHEMBL13680569 | 0.75 | NPC1 (0.54) | CCR1CCR8CYP2A6TGFBR1 | |
| SCHEMBL19626747 | 0.75 | CDC25A (0.58) | GRIA1CACNG8PDE3BPDE3ACDC25A | |
| SCHEMBL8264638 | 0.75 | GRIA1 (0.65) | GRIA1CACNG8PDE3BPDE3A | |
| SCHEMBL18190646 | 0.75 | GRIA1 (1.00) | GRIA1CACNG8PDE3BPDE3A | |
| SCHEMBL11990860 | 0.74 | CCR1 (0.68) | CCR1CCR8CYP2A6TGFBR1METAP2 | |
| SCHEMBL3422361 | 0.74 | CCR1 (0.75) | CCR1CCR8CYP2A6TGFBR1METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |