Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 13/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27439272 | 0.76 | MAOA (0.40) | MAOAMAOB | |
| SCHEMBL13680968 | 0.75 | ALDH1A1 (0.35) | MAOAMAOB | |
| SCHEMBL31432603 | 0.73 | CA12 (0.48) | MAOAMAOB | |
| SCHEMBL2056165 | 0.73 | CA12 (0.48) | MAOAMAOB | |
| SCHEMBL27646723 | 0.72 | MAOA (0.37) | MAOAMAOB | |
| SCHEMBL13680600 | 0.72 | GRIA1 (0.57) | — | |
| SCHEMBL13680699 | 0.71 | HSD17B1 (0.51) | GSK3B | |
| SCHEMBL13680592 | 0.70 | PRF1 (0.55) | MAOAMAOB | |
| SCHEMBL13680564 | 0.70 | CYP2A6 (0.41) | MAOAMAOB | |
| SCHEMBL13680623 | 0.69 | NPC1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |