Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 7/20 | 0.44 |
| ▸ | MTOR | P42345 | 5/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680712 | 0.88 | NPY5R (0.40) | CNR2POLBAOC3KDM4E | |
| SCHEMBL13680722 | 0.84 | TAAR1 (0.44) | KDM4E | |
| SCHEMBL6938016 | 0.75 | POLB (0.58) | CNR2POLBAOC3MTORPIK3R1 | |
| SCHEMBL13681022 | 0.74 | POLB (0.42) | CNR2POLBAOC3MTORPIK3R1 | |
| SCHEMBL13680715 | 0.73 | TDP1 (0.42) | POLBKMT2AKDM4E | |
| SCHEMBL24348371 | 0.72 | PRKAB2 (0.57) | MTORPIK3R1PIK3CAKCNH2KMT2A | |
| SCHEMBL15344111 | 0.72 | PIK3CA (0.53) | CNR2POLBAOC3MTORPIK3R1 | |
| SCHEMBL13680654 | 0.72 | AOC3 (0.54) | CNR2POLBAOC3MTORPIK3CA | |
| SCHEMBL13680682 | 0.71 | PIK3CA (0.52) | CNR2POLBAOC3MTORPIK3R1 | |
| SCHEMBL3409601 | 0.70 | PIK3CA (0.54) | CNR2POLBAOC3MTORPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |