Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680708 | 0.88 | CNR2 (0.48) | POLBKDM4EAOC3CNR2 | |
| SCHEMBL13680722 | 0.86 | TAAR1 (0.44) | CYP1A2CYP2C19MAPTKDM4EALDH1A1 | |
| SCHEMBL13680715 | 0.75 | TDP1 (0.42) | POLBMAPTSMN1; SMN2CHRM2CHRM4 | |
| SCHEMBL13681018 | 0.73 | SMN1; SMN2 (0.34) | POLBMAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL13680718 | 0.72 | ALDH1A1 (0.39) | POLBMAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL13680711 | 0.72 | ALDH1A1 (0.39) | MAPTSMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL436107 | 0.70 | POLB (0.47) | POLBMAPK1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL24349671 | 0.70 | PRKAB2 (0.60) | NPY5RPOLBMAPTMAPK1OPRK1 | |
| SCHEMBL24349478 | 0.70 | PRKAB2 (0.59) | NPY5RPOLBMAPTMAPK1OPRK1 | |
| SCHEMBL13680700 | 0.69 | MAP4K4 (0.41) | POLBMAPTSMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |