Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | CASP1 | P29466 | 3/20 | 0.39 |
| ▸ | CASP7 | P55210 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680712 | 0.86 | NPY5R (0.40) | ALDH1A1KDM4EMAPTCYP1A2CYP2C19 | |
| SCHEMBL13680708 | 0.84 | CNR2 (0.48) | KDM4E | |
| SCHEMBL4582837 | 0.75 | HTR1A (0.54) | TAAR1ALDH1A1KDM4EMAPTCHRNB2 | |
| SCHEMBL7991455 | 0.73 | ALDH1A1 (0.59) | TAAR1ALDH1A1KDM4ECHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL28966659 | 0.72 | ALDH1A1 (0.62) | TAAR1ALDH1A1KDM4ECHRNB2CHRNA4 | |
| SCHEMBL13680715 | 0.71 | TDP1 (0.42) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL9400977 | 0.71 | TAAR1 (0.64) | TAAR1ALDH1A1KDM4ECYP1A2CYP2C19 | |
| SCHEMBL4582036 | 0.71 | ADRB1 (0.54) | TAAR1ALDH1A1KDM4EHTR2CCYP1A2 | |
| SCHEMBL13680685 | 0.70 | KCNH2 (0.49) | TAAR1ALDH1A1KDM4EMAPTCYP1A2 | |
| SCHEMBL6787637 | 0.69 | HTR7 (0.54) | TAAR1ALDH1A1KDM4ECYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |