Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680702 | 0.79 | KDM4E (0.50) | GSK3BALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL13680715 | 0.77 | TDP1 (0.42) | GSK3BALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL13680718 | 0.74 | ALDH1A1 (0.39) | GSK3BALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL13680711 | 0.74 | ALDH1A1 (0.39) | GSK3BALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL13680568 | 0.73 | P4HTM (0.44) | GSK3BALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL13681005 | 0.73 | ALDH1A1 (0.39) | ALDH1A1KDM4ESMN1; SMN2MAPTKMT2A | |
| SCHEMBL13680716 | 0.73 | MAPT (0.39) | GSK3BALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL13680452 | 0.73 | GSK3B (0.61) | GSK3BALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL13680700 | 0.71 | MAP4K4 (0.41) | GSK3BALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL13680709 | 0.71 | GRM5 (0.37) | GSK3BALDH1A1KDM4ESMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |