Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 4/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MGAM | O43451 | 2/20 | 0.37 |
| ▸ | SI | P14410 | 2/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680702 | 0.85 | KDM4E (0.50) | MAPTMEN1KMT2AALOX15KDM4E | |
| SCHEMBL13680486 | 0.77 | MAPT (0.52) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL13681025 | 0.77 | MAPT (0.38) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL13680700 | 0.76 | MAP4K4 (0.41) | MAPTMEN1KMT2AALOX15KDM4E | |
| SCHEMBL13680506 | 0.73 | MAPK1 (0.51) | MAPTMEN1KMT2AALOX15KDM4E | |
| SCHEMBL8241210 | 0.73 | HPGD (0.46) | MAPTMEN1KMT2AALOX15KDM4E | |
| SCHEMBL13680713 | 0.73 | GSK3B (0.41) | MAPTMEN1KMT2AALOX15KDM4E | |
| SCHEMBL13680518 | 0.73 | MAPT (0.41) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL13680715 | 0.71 | TDP1 (0.42) | MAPTMEN1KMT2AALOX15KDM4E | |
| SCHEMBL13680657 | 0.71 | FAAH (0.46) | ALDH1A1HPGDMAPK1AAK1PIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |