Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | PKM | P14618 | 4/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680869 | 0.81 | PRMT1 (0.46) | PRMT1ALDH1A1MAPTKDM4EPKM | |
| SCHEMBL13680867 | 0.81 | ALDH1A1 (0.63) | ALDH1A1MAPTKDM4EPKMNPSR1 | |
| SCHEMBL13680901 | 0.81 | CYP1A2 (0.36) | PRMT1ALDH1A1MAPTKDM4EPKM | |
| SCHEMBL22042121 | 0.78 | PRMT1 (0.54) | PRMT1ALDH1A1MAPTKDM4EPKM | |
| SCHEMBL5124585 | 0.78 | ALDH1A1 (0.60) | PRMT1ALDH1A1MAPTKDM4ESCN10A | |
| SCHEMBL13680877 | 0.77 | HTR6 (0.52) | ALDH1A1MAPTKDM4EPKMNPSR1 | |
| SCHEMBL13680879 | 0.77 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4EPKMNPSR1 | |
| SCHEMBL13680887 | 0.76 | ALDH1A1 (0.46) | ALDH1A1MAPTKDM4EPKMNPSR1 | |
| SCHEMBL13680864 | 0.76 | ALDH1A1 (0.63) | ALDH1A1MAPTKDM4EPKMNPSR1 | |
| SCHEMBL13680866 | 0.76 | ALDH1A1 (0.60) | ALDH1A1MAPTKDM4EPKMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |