Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.64 |
| ▸ | GRM5 | P41594 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | BLM | P54132 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.64 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.64 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.64 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.52 |
| ▸ | GRIA1 | P42261 | 9/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 8/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quisqualate SCHEMBL136819 | 0.80 | CYP1A2 (1.00) | CYP1A2GRM5KDM4EBLMKMT2A | |
| Quisqualate SCHEMBL3674132 | 0.80 | CYP1A2 (1.00) | CYP1A2GRM5KDM4EBLMKMT2A | |
| Quisqualate SCHEMBL27790631 | 0.79 | CYP1A2 (0.97) | CYP1A2GRM5KDM4EBLMKMT2A | |
| SCHEMBL14688034 | 0.73 | GLA (0.42) | CYP1A2KMT2AMEN1ALDH1A1MAPK1 | |
| Quisqualate SCHEMBL7928396 | 0.71 | FOLH1 (0.64) | CYP1A2GRM5KDM4EBLMKMT2A | |
| SCHEMBL31532299 | 0.70 | GRM5 (1.00) | CYP1A2GRM5KDM4EBLMKMT2A | |
| SCHEMBL31532300 | 0.65 | GRM5 (0.55) | CYP1A2GRM5KDM4EBLMKMT2A | |
| SCHEMBL26036945 | 0.59 | GRM5 (0.58) | CYP1A2GRM5KDM4EBLMKMT2A | |
| SCHEMBL14255773 | 0.58 | ALDH1A1 (0.56) | CYP1A2GRM5KDM4EBLMKMT2A | |
| SCHEMBL12648453 | 0.56 | GRM5 (0.54) | CYP1A2GRM5KDM4EBLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2844756-A1 | MODULATING IMMUNE RESPONSES | Barber, Glen N. (US) | 2015-03-11 | — | — | EP | disclosed |
| WO-2013166000-A1 | MODULATING IMMUNE RESPONSES | BARBER GLEN N (US) | 2013-11-07 | — | — | WO | disclosed |