Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16200366 | 0.81 | METAP1 (0.44) | ADCY10RECQLSMN1; SMN2 | |
| SCHEMBL13683013 | 0.75 | THRB (0.42) | ADCY10RECQLSMN1; SMN2 | |
| SCHEMBL16200143 | 0.74 | SLC2A1 (0.47) | — | |
| SCHEMBL16200192 | 0.73 | IDO1 (0.36) | RECQL | |
| SCHEMBL13184118 | 0.72 | RECQL (0.41) | RECQL | |
| SCHEMBL26659412 | 0.72 | ADCY10 (0.38) | ADCY10RECQLSMN1; SMN2 | |
| SCHEMBL26659330 | 0.70 | ALDH1A1 (0.45) | SMN1; SMN2 | |
| SCHEMBL32686744 | 0.67 | ADCY10 (0.30) | ADCY10 | |
| SCHEMBL32686853 | 0.67 | ADCY10 (0.30) | ADCY10 | |
| SCHEMBL13683150 | 0.67 | ALDH1A1 (0.35) | ADCY10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720545-B1 | BICYCLIC AND BRIDGED NITROGEN HETEROCYCLES | CHEMOCENTRYX INC (US) | 2014-10-29 | — | — | EP | disclosed |
| US-7589199-B2 | Substituted piperazines | CHEMOCENTRYX, INC. (US) | 2009-09-15 | — | — | US | disclosed |