Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16200177 | 0.81 | CA1 (0.43) | ALDH1A1L3MBTL1RECQLNPC1RAB9A | |
| SCHEMBL16200162 | 0.81 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1PTGS1PTGS2 | |
| SCHEMBL14044137 | 0.80 | ALDH1A1 (0.32) | ALDH1A1L3MBTL1 | |
| SCHEMBL13430368 | 0.75 | LMNA (0.42) | ALDH1A1L3MBTL1RAB9A | |
| SCHEMBL16200200 | 0.75 | IDO1 (0.33) | IDO1 | |
| SCHEMBL16200157 | 0.74 | CYP2A13 (0.43) | ALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL13683155 | 0.73 | ADCY10 (0.36) | RECQL | |
| SCHEMBL16200156 | 0.72 | RECQL (0.38) | RECQL | |
| SCHEMBL3541488 | 0.71 | OPRL1 (0.54) | IDO1PTGS1PTGS2PDE2A | |
| SCHEMBL13184159 | 0.69 | POLB (0.39) | IDO1ALDH1A1L3MBTL1CYP2C9GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720545-B1 | BICYCLIC AND BRIDGED NITROGEN HETEROCYCLES | CHEMOCENTRYX INC (US) | 2014-10-29 | — | — | EP | disclosed |