Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | RGS12 | O14924 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL106499 | 0.81 | ADRA2A (0.43) | HCAR2ADRA2CKDM4EADRA2ALMNA | |
| SCHEMBL18800689 | 0.78 | HCAR2 (0.47) | HCAR2ADRA2CKDM4EADRA2ALMNA | |
| SCHEMBL297137 | 0.78 | HCAR2 (0.47) | HCAR2ADRA2CKDM4EADRA2ALMNA | |
| SCHEMBL16309500 | 0.77 | HCAR2 (0.39) | HCAR2ADRA2CKDM4EADRA2ALMNA | |
| SCHEMBL4195243 | 0.77 | HCAR2 (0.39) | HCAR2ADRA2CKDM4EADRA2ALMNA | |
| SCHEMBL10438594 | 0.76 | IDO1 (0.42) | ADRA2ALMNACHRM2ADRA1ACYP2D6 | |
| SCHEMBL8809690 | 0.74 | HCAR2 (0.37) | HCAR2ADRA2CKDM4EADRA2ALMNA | |
| SCHEMBL6906399 | 0.72 | TAAR1 (0.38) | HCAR2ADRA2CADRA2ALMNAFFAR1 | |
| SCHEMBL10889005 | 0.72 | THRB (0.37) | HCAR2ADRA2CKDM4EADRA2ALMNA | |
| SCHEMBL464725 | 0.72 | HCAR2 (0.45) | HCAR2ADRA2CKDM4EADRA2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1393401-B1 | NON-AQUEOUS ELECTROLYTE ADDITIVE FOR IMPROVING SAFETY AND LITHIUM ION SECONDARY BATTERY COMPRISING THE SAME | LG CHEMICAL LTD (KR) | 2012-11-14 | — | — | EP | disclosed |