Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL106499 | 0.81 | ADRA2A (0.43) | HCAR2ADRA2AADRA2CADRA2BTAAR1 | |
| SCHEMBL16309500 | 0.77 | HCAR2 (0.39) | HCAR2ADRA2AADRA2CADRA2BTAAR1 | |
| SCHEMBL13685162 | 0.77 | HCAR2 (0.43) | HCAR2TSHRADRA2AADRA2CADRA2B | |
| SCHEMBL8809690 | 0.74 | HCAR2 (0.37) | HCAR2ADRA2AADRA2CADRA2BTAAR1 | |
| SCHEMBL18800689 | 0.73 | HCAR2 (0.47) | HCAR2TSHRADRA2AADRA2CADRA2B | |
| SCHEMBL2761192 | 0.73 | HCAR2 (0.47) | HCAR2TSHRADRA2AADRA2CADRA2B | |
| SCHEMBL297137 | 0.73 | HCAR2 (0.47) | HCAR2TSHRADRA2AADRA2CADRA2B | |
| SCHEMBL10889005 | 0.72 | THRB (0.37) | HCAR2ADRA2AADRA2CADRA2BTAAR1 | |
| SCHEMBL6906399 | 0.72 | TAAR1 (0.38) | HCAR2ADRA2AADRA2CADRA2BTAAR1 | |
| SCHEMBL198133 | 0.72 | HCAR2 (0.45) | HCAR2TSHRADRA2AADRA2CADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2032588-B1 | METHOD FOR PREPARATION OF ALKOXYSILANES HAVING REDUCED HALIDE CONTENT | DOW CORNING (US) | 2012-08-08 | — | — | EP | disclosed |
| US-20090270646-A1 | METHOD FOR PREPARATION OF ALKOXYSILANES HAVING REDUCED HALIDE | DOW CORNING CORPORATION | 2009-10-29 | — | — | US | disclosed |
| EP-2032588-A2 | METHOD FOR PREPARATION OF ALKOXYSILANES HAVING REDUCED HALIDE CONTENT | Dow Corning Corporation (US) | 2009-03-11 | — | — | EP | disclosed |
| WO-2007149201-A2 | METHOD FOR PREPARATION OF ALKOXYSILANES HAVING REDUCED HALIDE CONTENT | DOW CORNING CORPORATION (US) | 2007-12-27 | — | — | WO | disclosed |
| EP-0974596-B1 | Method for preparation of alkoxysilanes having reduced halide content | DOW CORNING (US) | 2003-03-05 | — | — | EP | disclosed |
| EP-0974596-A2 | Method for preparation of alkoxysilanes having reduced halide content | DOW CORNING CORPORATION (US) | 2000-01-26 | — | — | EP | disclosed |
| US-5914421-A | Method for preparation of alkoxysilanes having reduced halide content | DOW CORNING CORPORATION (US) | 1999-06-22 | — | — | US | disclosed |