Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL106499 | 0.87 | ADRA2A (0.43) | HCAR2ADRA2AADRA2CADRA2BTAAR1 | |
| SCHEMBL7794349 | 0.76 | TAAR1 (0.37) | HCAR2ADRA2AADRA2CADRA2BTAAR1 | |
| SCHEMBL523682 | 0.75 | HCAR2 (0.42) | HCAR2ADRA2AADRA2CADRA2BTAAR1 | |
| SCHEMBL8502515 | 0.74 | HCAR2 (0.35) | HCAR2ADRA2AADRA2CADRA2BKDM4E | |
| SCHEMBL16309500 | 0.74 | HCAR2 (0.39) | HCAR2ADRA2AADRA2CADRA2BTAAR1 | |
| SCHEMBL4195243 | 0.74 | HCAR2 (0.39) | HCAR2ADRA2AADRA2CADRA2BTAAR1 | |
| SCHEMBL13685162 | 0.74 | HCAR2 (0.43) | HCAR2ADRA2AADRA2CADRA2BTAAR1 | |
| SCHEMBL8440986 | 0.73 | ADRA2A (0.35) | HCAR2ADRA2AADRA2CADRA2BTAAR1 | |
| SCHEMBL19809465 | 0.73 | GPR88 (0.35) | HCAR2ADRA2AADRA2BTAAR1CYP2D6 | |
| SCHEMBL8646050 | 0.71 | KDM4E (0.33) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3993839-A | ORGANO-SILOXY TITANIC ACID ESTERS | SHINETSU CHEMICAL COMPANY (JA) | 1976-11-23 | — | — | US | claimed |
| WO-1997003812-A1 | MOLDABLE ARTICLES OF PTFE/ELASTOMER COMPOSITES AND PROCESSES FOR MOLDING | W.L. GORE & ASSOCIATES, INC. (US) | 1997-02-06 | — | — | WO | disclosed |