Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP8 | P22894 | 2/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13686202 | 0.86 | MMP1 (0.32) | MMP1MMP2MMP8MMP13MMP3 | |
| SCHEMBL13684376 | 0.86 | MMP1 (0.37) | MMP1MMP2MMP8MMP13MEN1 | |
| SCHEMBL13686144 | 0.82 | — | — | |
| SCHEMBL13686136 | 0.81 | — | — | |
| SCHEMBL8278785 | 0.79 | MMP1 (0.33) | MMP1MMP2MMP8MMP13MEN1 | |
| SCHEMBL8194462 | 0.78 | CA1 (0.43) | — | |
| SCHEMBL8271464 | 0.74 | MMP1 (0.33) | MMP1MMP2MMP8MMP13MEN1 | |
| SCHEMBL8280382 | 0.74 | PER2 (0.33) | MMP1MMP2MMP8MMP13MEN1 | |
| SCHEMBL13127925 | 0.74 | ALDH1A1 (0.46) | MMP1MMP13MEN1KMT2A | |
| SCHEMBL13686148 | 0.73 | ABCC9 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592419-B2 | Macrocyclic inhibitors of hepatitis C virus NS3-serine protease | SCHERING CORPORATION (US) | 2009-09-22 | — | — | US | disclosed |