Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13684395 | 0.84 | ALDH1A1 (0.36) | TDP1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL13686139 | 0.81 | ADAM17 (0.31) | — | |
| SCHEMBL13932142 | 0.75 | RRM1 (0.33) | — | |
| SCHEMBL13686207 | 0.73 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL13316550 | 0.71 | TDP1 (0.34) | TDP1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL27439171 | 0.69 | CTSK (0.43) | — | |
| SCHEMBL12584802 | 0.68 | CHRNB2 (0.38) | TDP1LMNA | |
| SCHEMBL18195573 | 0.68 | TDP1 (0.43) | TDP1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL28714361 | 0.66 | TDP1 (0.42) | TDP1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL16493046 | 0.66 | TDP1 (0.38) | TDP1ALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592419-B2 | Macrocyclic inhibitors of hepatitis C virus NS3-serine protease | SCHERING CORPORATION (US) | 2009-09-22 | — | — | US | disclosed |