Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 7/20 | 0.34 |
| ▸ | NPC1 | O15118 | 6/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13691673 | 0.87 | CPB2 (0.37) | CPB2HPGDALDH1A1MAPT | |
| SCHEMBL13691765 | 0.72 | NPC1 (0.44) | CPB2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL13689403 | 0.71 | CPB2 (0.49) | CPB2 | |
| SCHEMBL13188847 | 0.71 | THRB (0.49) | HIF1ARAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL13691791 | 0.70 | ACR (0.56) | CPB2MAPT | |
| SCHEMBL8360611 | 0.65 | CPB2 (0.53) | CPB2 | |
| SCHEMBL23822827 | 0.60 | RAB9A (0.63) | HIF1ARAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL17079565 | 0.60 | HIF1A (0.78) | HIF1ARAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL18742006 | 0.60 | CPB2 (0.60) | CPB2 | |
| SCHEMBL18725757 | 0.60 | CPB2 (0.60) | CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009105823-A1 | 3-AMINOALKYL-1,4-DIAZEPAN-2-ONE MELANOCORTIN-5 RECEPTOR ANTAGONISTS | MIMETICA PTY LTD (AU) | 2009-09-03 | — | — | WO | disclosed |