Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13691856 | 0.88 | DRD2 (0.47) | MAPTNLRP3MEN1KMT2ACYP1A2 | |
| SCHEMBL13190967 | 0.84 | MAPT (0.47) | MAPTNLRP3MEN1KMT2ACYP1A2 | |
| SCHEMBL13189113 | 0.79 | UTS2R (0.38) | MEN1KMT2AUTS2RSMN1; SMN2DRD2 | |
| SCHEMBL13691792 | 0.78 | DRD2 (0.52) | MAPTNLRP3MEN1KMT2ACYP1A2 | |
| SCHEMBL13190970 | 0.78 | DRD2 (0.51) | MAPTNLRP3SMN1; SMN2DRD2DRD3 | |
| SCHEMBL13190971 | 0.77 | MC4R (0.48) | MAPTNLRP3MEN1KMT2ACYP1A2 | |
| SCHEMBL13689399 | 0.72 | LMNA (0.43) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL13689519 | 0.72 | LMNA (0.48) | MEN1KMT2AUTS2RLMNASMN1; SMN2 | |
| SCHEMBL13189116 | 0.72 | UTS2R (0.39) | MEN1KMT2ACYP1A2UTS2RALDH1A1 | |
| SCHEMBL13691674 | 0.72 | DRD2 (0.41) | MAPTMEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009105823-A1 | 3-AMINOALKYL-1,4-DIAZEPAN-2-ONE MELANOCORTIN-5 RECEPTOR ANTAGONISTS | MIMETICA PTY LTD (AU) | 2009-09-03 | — | — | WO | disclosed |