Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.63 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.63 |
| ▸ | GLS | O94925 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4687548 | 0.85 | FFAR2 (0.74) | FFAR2KDM4ELMNAUSP2TSHR | |
| Hydrochloric Acid SCHEMBL29855979 | 0.84 | FFAR2 (0.72) | FFAR2KDM4ELMNAUSP2TSHR | |
| SCHEMBL23657933 | 0.78 | PRKACA (0.61) | MAPK8FFAR2GLSLMNAUSP2 | |
| SCHEMBL11627595 | 0.78 | ROCK1 (0.61) | FFAR2GLSKDM4ELMNAUSP2 | |
| SCHEMBL13694242 | 0.78 | GLS (0.59) | MAPK8GLSCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL27578137 | 0.78 | CCNE1 (0.76) | MAPK8GLSCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7876992 | 0.78 | HSPA5 (0.52) | MAPK8CYP1A2CYP3A4CYP2C9KDM4E | |
| SCHEMBL20014229 | 0.76 | CCNE1 (0.62) | MAPK8GLSCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5022365 | 0.76 | ADORA2A (0.59) | MAPK8GLSCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL362394 | 0.76 | ALDH1A1 (0.66) | MAPK8CYP1A2CYP3A4CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221647-A1 | N-(2-THIAZOLYL)-AMIDE DERIVATIVES AS GSK-3 INHIBITORS | NOSCIRA, S.A. (ES) | 2009-09-03 | — | — | US | disclosed |
| US-20090221647-A1 | N-(2-THIAZOLYL)-AMIDE DERIVATIVES AS GSK-3 INHIBITORS | NOSCIRA, S.A. (ES) | 2009-09-03 | — | — | US | disclosed |
| WO-2007125110-A1 | N- ( 2-THIAZOLYL) -AMIDE DERIVATIVES AS GSK-3 INHIBITORS | NOSCIRA, S.A. (ES) | 2007-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221647-A1 | N-(2-THIAZOLYL)-AMIDE DERIVATIVES AS GSK-3 INHIBITORS | GSK3B, GSK3A, GSKIP | MAPK8 1077/4885FFAR2 1617/4885GLS 661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.