Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.67 |
| ▸ | TYMP | P19971 | 3/20 | 0.64 |
| ▸ | GSK3A | P49840 | 2/20 | 0.62 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.62 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.62 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.56 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HINT1 | P49773 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALB | P02768 | 1/20 | 0.51 |
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.50 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.50 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.50 |
| ▸ | GAPDH | P04406 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15482193 | 1.00 | P2RX3 (0.67) | P2RX3TYMPGSK3ARPS6KA3MAPK14 | |
| SCHEMBL27250729 | 0.92 | P2RX3 (0.60) | P2RX3TYMPGSK3ARPS6KA3MAPK14 | |
| Inosine SCHEMBL13012212 | 0.89 | PAX8 (0.69) | P2RX3TYMPGSK3ARPS6KA3MAPK14 | |
| Inosine SCHEMBL12964365 | 0.89 | PAX8 (0.69) | P2RX3TYMPGSK3ARPS6KA3MAPK14 | |
| Inosine SCHEMBL6933022 | 0.89 | PAX8 (0.69) | P2RX3TYMPGSK3ARPS6KA3MAPK14 | |
| Inosine SCHEMBL13062153 | 0.89 | PAX8 (0.69) | P2RX3TYMPGSK3ARPS6KA3MAPK14 | |
| Inosine SCHEMBL18249508 | 0.89 | PAX8 (0.69) | P2RX3TYMPGSK3ARPS6KA3MAPK14 | |
| Inosine SCHEMBL10001664 | 0.89 | PAX8 (0.69) | P2RX3TYMPGSK3ARPS6KA3MAPK14 | |
| Inosine SCHEMBL16707275 | 0.89 | PAX8 (0.69) | P2RX3TYMPGSK3ARPS6KA3MAPK14 | |
| Inosine SCHEMBL6748953 | 0.89 | PAX8 (0.69) | P2RX3TYMPGSK3ARPS6KA3MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227544-A1 | Bone Targeted Therapeutics and Methods of Making and Using the Same | MBC PHARMA, INC. (US) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227544-A1 | Bone Targeted Therapeutics and Methods of Making and Using the Same | SOST, BPGM, BST2 | P2RX3 870/4885TYMP 412/4885GSK3A 3562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.