Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.58 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4085131 | 0.84 | CYP3A4 (0.58) | ALDH1A1CYP3A4CYP2D6CYP1A2CLK4 | |
| SCHEMBL14641717 | 0.82 | LMNA (0.51) | ALDH1A1CYP3A4CYP2D6CYP1A2CLK4 | |
| SCHEMBL427012 | 0.82 | ALDH1A1 (0.58) | ALDH1A1CYP3A4CYP2D6CYP1A2CLK4 | |
| SCHEMBL3322382 | 0.81 | KDM4E (0.53) | ALDH1A1CYP3A4CYP2D6CYP1A2CLK4 | |
| SCHEMBL11988213 | 0.77 | DRD2 (0.57) | ALDH1A1CYP3A4CYP2D6CYP1A2CLK4 | |
| SCHEMBL2831921 | 0.76 | ABL1 (0.49) | ALDH1A1CYP3A4CYP2D6CYP1A2CLK4 | |
| SCHEMBL12015770 | 0.76 | ABL1 (0.47) | ALDH1A1CYP3A4CYP2D6CYP1A2CLK4 | |
| SCHEMBL11988642 | 0.76 | FGFR1 (0.49) | ALDH1A1CYP3A4CYP2D6CYP1A2CLK4 | |
| SCHEMBL14068215 | 0.76 | CYP1A2 (0.60) | ALDH1A1CYP3A4CYP2D6CYP1A2CLK4 | |
| SCHEMBL15260237 | 0.76 | CYP1A2 (0.67) | ALDH1A1CYP3A4CYP2D6CYP1A2CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227586-A1 | 2-ANILINO-4-(HETEROCYCLIC)AMINO-PYRIMIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227586-A1 | 2-ANILINO-4-(HETEROCYCLIC)AMINO-PYRIMIDINES | PRKCA, PRKCG, PRKCH | ALDH1A1 4216/4885CYP3A4 3766/4885CYP2D6 3799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.