Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2933753 | 0.86 | HTR1A (0.32) | TDP1 | |
| SCHEMBL11858617 | 0.77 | TDP1 (0.43) | TDP1FFAR3ALDH1A1 | |
| SCHEMBL1193421 | 0.77 | CCNE2 (0.35) | — | |
| SCHEMBL11038975 | 0.77 | TDP1 (0.38) | TDP1 | |
| SCHEMBL13701324 | 0.75 | TDP1 (0.41) | TDP1 | |
| SCHEMBL19704476 | 0.75 | — | — | |
| SCHEMBL14037208 | 0.73 | CYP2C19 (0.42) | TDP1ALDH1A1 | |
| SCHEMBL12510344 | 0.73 | — | — | |
| SCHEMBL3461929 | 0.72 | — | — | |
| SCHEMBL2223767 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9051330-B2 | Dithiolopyrrolones with therapeutic activity | WELICHEM BIOTECH INC. (CA) | 2015-06-09 | — | — | US | disclosed |
| US-20090221574-A1 | 5-Lipoxygenase-Activating Protein (FLAP) Inhibitors | AMIRA PHARMACEUTICALS, INC. (US) | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221574-A1 | 5-Lipoxygenase-Activating Protein (FLAP) Inhibitors | ALOX5, ALOX15B, ALOX15 | TDP1 1428/4885FFAR3 1431/4885ALDH1A1 1358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.