Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 7/20 | 0.36 |
| ▸ | HTR7 | P34969 | 5/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.32 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14496822 | 0.85 | PLA2G2A (0.39) | PLA2G2APLA2G10PLA2G1BPLA2G5CYP11B1 | |
| SCHEMBL13698684 | 0.84 | POLB (0.35) | — | |
| SCHEMBL3202650 | 0.82 | PLA2G2A (0.39) | PLA2G2APLA2G10PLA2G1BPLA2G5KCNA5 | |
| SCHEMBL3202635 | 0.82 | PLA2G2A (0.39) | PLA2G2APLA2G10PLA2G1BPLA2G5KCNA5 | |
| SCHEMBL3199332 | 0.81 | PLA2G2A (0.41) | PLA2G2AHTR7PLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL3199322 | 0.81 | PLA2G2A (0.41) | PLA2G2AHTR7PLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL3207332 | 0.80 | HTR7 (0.38) | PLA2G2AHTR7PLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL13485087 | 0.79 | HTR7 (0.34) | PLA2G2AHTR7PLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL13484986 | 0.76 | PLA2G2A (0.36) | PLA2G2APLA2G10PLA2G1BPLA2G5KCNA5 | |
| SCHEMBL13484987 | 0.75 | PLA2G2A (0.35) | PLA2G2APLA2G10PLA2G1BPLA2G5CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090239896-A1 | AZAINDOLE COMPOUNDS AND USE THEREOF AS PHOSPHOLIPASE-A2 INHIBITORS | ILYPSA, INC. | 2009-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239896-A1 | AZAINDOLE COMPOUNDS AND USE THEREOF AS PHOSPHOLIPASE-A2 INHIBITORS | PLA2G5, PLA2G4A, PLA2G3 | PLA2G2A 15/4885HTR7 107/4885PLA2G10 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.