Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 4/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RHOC | P08134 | 3/20 | 0.42 |
| ▸ | RHOA | P61586 | 3/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13699182 | 0.80 | LMNA (0.48) | NAMPTHDAC3HDAC1TP53BP1ALDH1A1 | |
| SCHEMBL5543873 | 0.71 | NAMPT (0.67) | NAMPTHDAC3HDAC1EPHX2SIGMAR1 | |
| SCHEMBL5546309 | 0.71 | NAMPT (0.67) | NAMPTHDAC3HDAC1EPHX2SIGMAR1 | |
| SCHEMBL5515823 | 0.71 | NAMPT (0.67) | NAMPTHDAC3HDAC1EPHX2SIGMAR1 | |
| SCHEMBL20707157 | 0.71 | NAMPT (0.67) | NAMPTHDAC3HDAC1EPHX2SIGMAR1 | |
| SCHEMBL5536198 | 0.70 | NAMPT (0.64) | NAMPTHDAC3HDAC1ALDH1A1EPHX2 | |
| SCHEMBL5540070 | 0.69 | NAMPT (0.73) | NAMPTHDAC3HDAC1ALDH1A1 | |
| SCHEMBL13699130 | 0.69 | CA2 (0.66) | HDAC3HDAC1RHOCRHOAEPHX2 | |
| SCHEMBL13699124 | 0.68 | CA2 (0.52) | NAMPTHDAC3HDAC1TP53BP1ALDH1A1 | |
| SCHEMBL19133513 | 0.67 | NAMPT (0.61) | NAMPTHDAC3HDAC1EPHX2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009113704-A2 | FLUORINE-CONTAINING COMPOUND AND METHOD FOR DETECTING BIOMOLECULE USING THE SAME | KYOTO UNIVERSITY (JP) | 2009-09-17 | — | — | WO | disclosed |