Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13240239 | 0.89 | KIF11 (0.36) | ALDH1A1MAPTKDM4EL3MBTL1MEN1 | |
| SCHEMBL13488507 | 0.89 | MAPT (0.35) | ALDH1A1MAPTKDM4EL3MBTL1MEN1 | |
| SCHEMBL13694878 | 0.84 | S1PR1 (0.36) | ALDH1A1MAPTKDM4EL3MBTL1HPGD | |
| SCHEMBL3027348 | 0.83 | HRH3 (0.36) | ALDH1A1MAPTKDM4EL3MBTL1HPGD | |
| SCHEMBL3037414 | 0.83 | TP53 (0.37) | TP53THRBRAB9AMAPK1 | |
| SCHEMBL3028310 | 0.82 | CNR1 (0.34) | ALDH1A1MAPTKDM4EL3MBTL1MEN1 | |
| SCHEMBL3031793 | 0.82 | HRH3 (0.38) | ALDH1A1MAPTKDM4EL3MBTL1HPGD | |
| SCHEMBL13694880 | 0.82 | HTR7 (0.32) | ALDH1A1MAPTKDM4EL3MBTL1MEN1 | |
| SCHEMBL3036691 | 0.81 | THRA (0.37) | TP53GAATHRBKMT2ALMNA | |
| SCHEMBL3207524 | 0.80 | ACHE (0.41) | ALDH1A1MAPTKDM4EL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2098520-A1 | Photochromic dichroic naphtho-pyrans and optical articles containing them | Essilor International (Compagnie Générale D'Optique) (FR) | 2009-09-09 | — | — | EP | disclosed |