SCHEMBL13700487

SCHEMBL13700487

O=C(ON1C(=O)CC(c2ccccc2)(c2ccccc2)C1=O)ON1C(=O)CC(c2ccccc2)(c2ccccc2)C1=O

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
AKR1C1 Q04828 1/20 0.33
ATM Q13315 2/20 0.32
PPME1 Q9Y570 1/20 0.32
MITF O75030 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
LMNA P02545 2/20 0.32
CNR1 P21554 1/20 0.32
HTT P42858 1/20 0.32
HDAC9 Q9UKV0 1/20 0.32
HSD11B1 P28845 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13700501 0.88 ALDH1A1 (0.33) ALDH1A1AKR1C1ATMPPME1HSD11B1
SCHEMBL7952846 0.78 SRC (0.33) ALDH1A1LMNA
SCHEMBL15657386 0.68 CFTR (0.45) ALDH1A1AKR1C1MEN1KMT2ALMNA
SCHEMBL14359857 0.62 ADRA1D (0.44) MEN1KMT2A
SCHEMBL7793255 0.62 ALDH1A1 (0.38) ALDH1A1ATMPPME1HSD11B1
SCHEMBL14359538 0.62 ADRA1D (0.43) MEN1KMT2A
SCHEMBL10972047 0.62 ADRA1D (0.43)
SCHEMBL7380213 0.61 HSD11B1 (0.45) ALDH1A1AKR1C1MEN1KMT2AHSD11B1
SCHEMBL2177419 0.61 ALDH1A1 (0.50) ALDH1A1MEN1KMT2A
SCHEMBL7780925 0.61 MAPK1 (0.47) ALDH1A1ATMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7585925-B2 Method of producing a polymer network DR. GOTTSCHALL INSTRUCTION GESELLSCHAFT FUR TECHNISCHE CHROMATOGRAPHIE MBH (DE) 2009-09-08 US disclosed
US-7585925-B2 Method of producing a polymer network DR. GOTTSCHALL INSTRUCTION GESELLSCHAFT FUR TECHNISCHE CHROMATOGRAPHIE MBH (DE) 2009-09-08 US disclosed
US-20080058501-A1 Method of Producing a Polymer Network GOTTSCHALL KLAUS 2008-03-06 US disclosed
US-20080058501-A1 Method of Producing a Polymer Network GOTTSCHALL KLAUS 2008-03-06 US disclosed
US-7291686-B1 Method of producing polymer network DR. GOTTSCHALL INSTRUCTION GESELLSCHAFT FUR TECHNISCHE CHROMATOGRAPHIE MBH (DE) 2007-11-06 US disclosed
US-7291686-B1 Method of producing polymer network DR. GOTTSCHALL INSTRUCTION GESELLSCHAFT FUR TECHNISCHE CHROMATOGRAPHIE MBH (DE) 2007-11-06 US disclosed