SCHEMBL13700677

SCHEMBL13700677

CC1=C(C)CCC(c2ccc(N(C)C)cc2)=C1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.42
TSHR P16473 3/20 0.42
ALOX15 P16050 2/20 0.42
HSD17B10 Q99714 2/20 0.42
MAPT P10636 5/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
MAPK1 P28482 3/20 0.35
CYP3A4 P08684 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
TP53 P04637 2/20 0.35
CYP1A2 P05177 1/20 0.35
KDM4E B2RXH2 2/20 0.34
APP P05067 3/20 0.34
NPC1 O15118 2/20 0.34
HPGD P15428 2/20 0.34
RAB9A P51151 2/20 0.34
NOTUM Q6P988 1/20 0.34
PABPC1 P11940 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13849372 0.80 ALDH1A1 (0.38) ALDH1A1MAPTSMN1; SMN2MAPK1CYP3A4
SCHEMBL24923799 0.78 ALDH1A1 (0.44) ALDH1A1TSHRALOX15HSD17B10MAPT
SCHEMBL13760183 0.73 BACE1 (0.46) ALDH1A1MAPTSMN1; SMN2MAPK1TDP1
SCHEMBL13856263 0.72 CYP2A6 (0.43) ALDH1A1TSHRHSD17B10NOTUM
SCHEMBL14089331 0.72 CYP1A2 (0.38) ALDH1A1TSHRALOX15HSD17B10MAPT
SCHEMBL13368892 0.70 PTGS2 (0.37) ALDH1A1CYP3A4CYP1A2NOTUMPGR
SCHEMBL14089322 0.68 MAPT (0.41) ALDH1A1TSHRALOX15HSD17B10MAPT
SCHEMBL124209 0.68 ALDH1A1 (0.79) ALDH1A1TSHRALOX15HSD17B10MAPT
SCHEMBL11547412 0.68 ALDH1A1 (0.79) ALDH1A1TSHRALOX15HSD17B10MAPT
SCHEMBL13856264 0.67 RAB9A (0.47) ALDH1A1TSHRALOX15HSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2103665-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2009-09-23 EP disclosed
EP-2085450-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2009-08-05 EP disclosed