SCHEMBL13760183

SCHEMBL13760183

COc1ccc(C2=CC(C)=C(C)CC2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 2/20 0.46
ALDH1A1 P00352 2/20 0.45
MEN1 O00255 2/20 0.45
MAPK1 P28482 2/20 0.45
KMT2A Q03164 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
PTGS2 P35354 1/20 0.42
KDM4E B2RXH2 1/20 0.42
MAPT P10636 1/20 0.42
PKM P14618 1/20 0.42
MCL1 Q07820 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ACHE P22303 1/20 0.41
ESR2 Q92731 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6319811 0.80 ALDH1A1 (0.60) BACE1ALDH1A1MEN1MAPK1KMT2A
SCHEMBL3961649 0.73 ALDH1A1 (0.57) BACE1ALDH1A1MEN1MAPK1KMT2A
SCHEMBL13700677 0.73 ALDH1A1 (0.42) ALDH1A1MAPK1SMN1; SMN2KDM4EMAPT
SCHEMBL13856263 0.72 CYP2A6 (0.43) ALDH1A1CA12CA1CA2CA9
SCHEMBL17480605 0.72 ME2 (0.50) BACE1ALDH1A1MEN1MAPK1KMT2A
SCHEMBL5978532 0.71 CA12 (0.44) BACE1ALDH1A1MEN1MAPK1KMT2A
SCHEMBL29080015 0.70 MAPT (0.47) BACE1ALDH1A1MEN1MAPK1KMT2A
SCHEMBL13368892 0.70 PTGS2 (0.37) ALDH1A1PTGS2CYP11B1CYP11B2
SCHEMBL9054140 0.69 PTGS2 (0.78) PTGS2CYP11B1CYP11B2
SCHEMBL8972556 0.69 PTGS2 (0.56) BACE1ALDH1A1SMN1; SMN2PTGS2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2085450-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2009-08-05 EP disclosed