SCHEMBL13856263

SCHEMBL13856263

CC1=C(C)CCC(c2ccc(C#N)cc2)=C1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.43
ALDH1A1 P00352 1/20 0.43
KIF11 P52732 2/20 0.40
MMP3 P08254 1/20 0.39
PTGS2 P35354 1/20 0.38
GAA P10253 1/20 0.38
CYP11B2 P19099 5/20 0.37
CYP11B1 P15538 1/20 0.35
CA12 O43570 2/20 0.34
CA2 P00918 2/20 0.34
CA9 Q16790 2/20 0.34
CA3 P07451 1/20 0.34
CA6 P23280 1/20 0.34
CA14 Q9ULX7 1/20 0.34
CA1 P00915 1/20 0.34
TSHR P16473 1/20 0.34
HSD17B10 Q99714 1/20 0.34
HRH2 P25021 1/20 0.34
HRH1 P35367 1/20 0.34
HRH3 Q9Y5N1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1339032 0.73 CYP2A6 (0.42) CYP2A6ALDH1A1KIF11MMP3PTGS2
SCHEMBL13700677 0.72 ALDH1A1 (0.42) ALDH1A1TSHRHSD17B10NOTUM
SCHEMBL13760183 0.72 BACE1 (0.46) ALDH1A1PTGS2CYP11B2CYP11B1CA12
SCHEMBL13368892 0.69 PTGS2 (0.37) ALDH1A1PTGS2GAACYP11B2CYP11B1
SCHEMBL20749368 0.68 CYP2A6 (0.61) CYP2A6ALDH1A1KIF11MMP3PTGS2
SCHEMBL13849372 0.68 ALDH1A1 (0.38) ALDH1A1
SCHEMBL396846 0.67 MMP3 (0.74) CYP2A6ALDH1A1KIF11MMP3CYP11B2
Water SCHEMBL11055485 0.67 MMP3 (0.74) CYP2A6ALDH1A1KIF11MMP3CYP11B2
SCHEMBL26246 0.67 MMP3 (0.74) CYP2A6ALDH1A1KIF11MMP3CYP11B2
SCHEMBL13063633 0.67 MMP3 (0.74) CYP2A6ALDH1A1KIF11MMP3CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2055710-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2009-05-06 EP disclosed