Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 2/20 | 0.62 |
| ▸ | HMGCR | P04035 | 1/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.62 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CPT2 | P23786 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.31 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13701363 | 0.83 | ALDH1A1 (0.46) | ADRA1AHMGCRCHRM1TBXA2RCYP2C19 | |
| SCHEMBL30476304 | 0.81 | CYP2C19 (0.45) | ADRA1AHMGCRCHRM1TBXA2RCYP2C19 | |
| SCHEMBL8221292 | 0.80 | CYP2C19 (0.46) | ADRA1AHMGCRCHRM1TBXA2RCYP2C19 | |
| Meglutol SCHEMBL8718194 | 0.79 | HMGCR (1.00) | ADRA1AHMGCRCHRM1TBXA2RCYP2C19 | |
| Meglutol SCHEMBL28443 | 0.79 | HMGCR (1.00) | ADRA1AHMGCRCHRM1TBXA2RCYP2C19 | |
| SCHEMBL3894338 | 0.78 | CYP2C19 (0.45) | ADRA1AHMGCRCHRM1TBXA2RCYP2C19 | |
| SCHEMBL10192956 | 0.76 | HMGCR (0.71) | ADRA1AHMGCRCHRM1TBXA2RCYP2C19 | |
| SCHEMBL28715378 | 0.76 | HMGCR (0.64) | ADRA1AHMGCRCHRM1TBXA2RCYP2C19 | |
| T-Butylacetic Acid SCHEMBL11723391 | 0.76 | ADRA1A (0.44) | ADRA1AHMGCRCHRM1TBXA2RCYP2C19 | |
| SCHEMBL17037299 | 0.74 | HMGCR (0.68) | ADRA1AHMGCRCHRM1TBXA2RCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233274-A1 | DRUG DEVELOPMENT TARGET PROTEIN AND TARGET GENE, AND METHOD OF SCREENING | REVERSE PROTEOMICS RESEARCH INSTITUTE CO. (JP) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233274-A1 | DRUG DEVELOPMENT TARGET PROTEIN AND TARGET GENE, AND METHOD OF SCREENING | NCS1, PRSS12, TPX2 | ADRA1A 4581/4885HMGCR 2567/4885CHRM1 4652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.