Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.59 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.59 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.59 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.51 |
| ▸ | FEN1 | P39748 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303110 | 0.88 | MAPT (0.54) | CHRNB2CHRNB4CHRNA3CHRNA4MEN1 | |
| SCHEMBL10172579 | 0.85 | KAT6A (0.56) | CHRNB2CHRNB4CHRNA3CHRNA4MEN1 | |
| SCHEMBL11495204 | 0.85 | CHRNB2 (0.54) | CHRNB2CHRNB4CHRNA3CHRNA4MEN1 | |
| SCHEMBL7305639 | 0.83 | MAPT (0.49) | CHRNB2CHRNB4CHRNA3CHRNA4MEN1 | |
| SCHEMBL6748722 | 0.82 | MAPT (0.61) | MEN1KMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL530569 | 0.82 | CHRNB2 (0.59) | CHRNB2CHRNB4CHRNA3CHRNA4MEN1 | |
| SCHEMBL7606412 | 0.81 | L3MBTL1 (0.64) | CHRNB2CHRNB4CHRNA3CHRNA4MEN1 | |
| SCHEMBL9383059 | 0.80 | ALOX5AP (0.56) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL14357551 | 0.79 | ALDH1A1 (0.56) | MEN1KMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL29643318 | 0.79 | ALDH1A1 (0.56) | MEN1KMT2AMAPTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117362190-A | Preparation method of polysubstituted olefin | 广东工业大学 | 2024-01-09 | — | — | CN | disclosed |
| US-20090227588-A1 | Substituted pyrazole compounds useful as soluble epoxide hyrolase inhibitors | FLECK ROMAN WOLFGANG | 2009-09-10 | — | — | US | disclosed |
| US-20090227588-A1 | Substituted pyrazole compounds useful as soluble epoxide hyrolase inhibitors | FLECK ROMAN WOLFGANG | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227588-A1 | Substituted pyrazole compounds useful as soluble epoxide hyrolase inhibitors | EPHX1, EPHX2, EPX | CHRNB2 3917/4885CHRNB4 3841/4885CHRNA3 3378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.