Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13702368 | 0.87 | GPR132 (0.50) | LMNAALDH1A1GPR132SMPD1KMT2A | |
| SCHEMBL13702127 | 0.85 | GPR132 (0.56) | LMNAALDH1A1GPR132SMPD1KMT2A | |
| SCHEMBL13702302 | 0.85 | HPGD (0.53) | LMNAGPR132SMPD1KMT2AMEN1 | |
| SCHEMBL13701726 | 0.83 | LMNA (0.58) | LMNAALDH1A1GPR132SMPD1KMT2A | |
| SCHEMBL13701702 | 0.82 | LMNA (0.55) | LMNAALDH1A1GPR132SMPD1KMT2A | |
| SCHEMBL3778535 | 0.81 | KMT2A (0.58) | GPR132KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL14507861 | 0.80 | OPRM1 (0.54) | GPR132KMT2ASMN1; SMN2KDM4ETDP1 | |
| SCHEMBL13701720 | 0.80 | LMNA (0.67) | LMNAALDH1A1SMPD1KMT2AMEN1 | |
| SCHEMBL13701712 | 0.79 | LMNA (0.65) | LMNAALDH1A1SMPD1KMT2AMEN1 | |
| SCHEMBL13701753 | 0.78 | CYP1A2 (0.61) | LMNAALDH1A1KMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227588-A1 | Substituted pyrazole compounds useful as soluble epoxide hyrolase inhibitors | FLECK ROMAN WOLFGANG | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227588-A1 | Substituted pyrazole compounds useful as soluble epoxide hyrolase inhibitors | EPHX1, EPHX2, EPX | LMNA 1843/4885ALDH1A1 376/4885GPR132 3141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.