Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | MAOB | P27338 | 1/20 | 0.65 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.62 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.59 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.57 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13753371 | 0.88 | ALDH1A1 (0.71) | KMT2AMAOBNR1H4ALDH1A1SMN1; SMN2 | |
| SCHEMBL8803623 | 0.88 | KMT2A (0.58) | KMT2AMAOBNR1H4SMPD1ADRB2 | |
| SCHEMBL11213011 | 0.85 | KMT2A (0.69) | KMT2ANR1H4SMPD1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13702374 | 0.85 | KMT2A (0.69) | KMT2ANR1H4SMPD1ALDH1A1SMN1; SMN2 | |
| SCHEMBL24850053 | 0.84 | KMT2A (0.61) | KMT2AMAOBNR1H4SMPD1ADRB2 | |
| SCHEMBL13701720 | 0.81 | LMNA (0.67) | KMT2ANR1H4SMPD1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27913517 | 0.81 | KMT2A (0.78) | KMT2ANR1H4SMPD1ADRB2ADRB1 | |
| SCHEMBL13702128 | 0.80 | MAOB (0.57) | MAOBLMNA | |
| SCHEMBL2340354 | 0.80 | KMT2A (0.71) | KMT2ANR1H4SMPD1ADRB2ADRB1 | |
| SCHEMBL13702183 | 0.80 | GPR132 (0.73) | KMT2AMAOBNR1H4SMPD1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227588-A1 | Substituted pyrazole compounds useful as soluble epoxide hyrolase inhibitors | FLECK ROMAN WOLFGANG | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227588-A1 | Substituted pyrazole compounds useful as soluble epoxide hyrolase inhibitors | EPHX1, EPHX2, EPX | KMT2A 3792/4885MAOB 475/4885NR1H4 346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.