SCHEMBL13712970

SCHEMBL13712970

COc1cc2c(cc1OCC(C)O)C1(CC(C)(C)c3cc(CO)c(OCC(C)O)cc31)CC2(C)C

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.38
PDE4A P27815 1/20 0.34
PDE4B Q07343 1/20 0.34
PDE4C Q08493 1/20 0.34
PDE4D Q08499 1/20 0.34
POLA1 P09884 2/20 0.32
AGTR1 P30556 1/20 0.30
LMNA P02545 1/20 0.30
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13712358 0.91 LMNA (0.33) ALOX15PDE4APDE4BPDE4CPDE4D
SCHEMBL13447603 0.83 PDE4A (0.49) ALOX15PDE4APDE4BPDE4CPDE4D
SCHEMBL17264203 0.78 ALOX15 (0.43) ALOX15PDE4APDE4BPDE4CPDE4D
SCHEMBL14539423 0.75 ALOX15 (0.40) ALOX15PDE4APDE4BPDE4CPDE4D
SCHEMBL11136773 0.74 CA12 (0.41) ALOX15
SCHEMBL13712351 0.71 LMNA (0.44) LMNA
SCHEMBL11220334 0.70 ALOX15 (0.51) ALOX15PDE4APDE4BPDE4CPDE4D
SCHEMBL12110373 0.69 FTO (0.38) LMNA
SCHEMBL4464547 0.67 FTO (0.39) ALOX15LMNA
SCHEMBL8113215 0.67 ALK (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7582355-B2 Optical unit using plastic lenses FUJIFILM CORPORATION (JP) 2009-09-01 US disclosed