Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7279830 | 0.83 | KMT2A (0.47) | KMT2ASRCCYP2D6LMNACYP1A2 | |
| SCHEMBL27309507 | 0.79 | KMT2A (0.44) | KMT2ASRCCYP2D6LMNACYP1A2 | |
| SCHEMBL2401919 | 0.79 | KMT2A (0.64) | KMT2ALMNA | |
| SCHEMBL9217848 | 0.79 | KMT2A (0.44) | KMT2ASRCCYP2D6LMNACYP1A2 | |
| SCHEMBL2078143 | 0.79 | KMT2A (0.64) | KMT2ALMNA | |
| SCHEMBL529525 | 0.78 | L3MBTL1 (0.56) | KMT2ASRCCYP2D6LMNACYP1A2 | |
| SCHEMBL27793738 | 0.78 | L3MBTL1 (0.56) | KMT2ASRCCYP2D6LMNACYP1A2 | |
| SCHEMBL8528299 | 0.77 | LMNA (0.58) | KMT2ASRCCYP2D6LMNACYP1A2 | |
| SCHEMBL29136154 | 0.77 | LMNA (0.58) | KMT2ASRCCYP2D6LMNACYP1A2 | |
| SCHEMBL9051580 | 0.77 | KMT2A (0.45) | KMT2ASRCCYP2D6LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465880-B1 | 5-SULPHANYL-4H-1,2,4-TRIAZOLE DERIVATIVES AND THEIR USE TO TREAT DISORDERS ASSOCIATED WITH SOMATOSTATINE | IPSEN PHARMA (FR) | 2009-08-05 | — | — | EP | disclosed |